Ketoconazole in dogs is an antifungal drug effective against fungi of the lymph nodes, skin, nails, respiratory system, bones and other parts of the body of your pet. A shampoo that mixes Ketoconazole with Chlorhexidine is used to treat fungal and bacterial infections of the skin.
Ketoconazole is an antifungal medicine used predominantly to treat fungal infections, although it has additional properties that can help in the treatment of truncal alopecia.
In the past it was used for Cushing’s disease, but this is no longer common since medicine can put additional stress on the liver, even leading to liver failure in rare cases.
It is derived from the organic compound imidazole and works by inhibiting the vital process for the growth of fungi. In large doses it can puncture holes in the cell membrane of fungal structures destroying them, causing the loss of essential components.
If you notice that your dog becomes irregular and large amounts of hair are shed you should talk to the veterinarian for diagnosis, as you may have scabies or lupus.
Other forms of Ketoconazole in dogs are itraconazole and fluconazole, they have been produced to improve the number of side effects and the effectiveness of certain types of infections. Some fungi have shown resistance to Ketoconazole, such as Candida albicans.
The imidazole derivatives, including ketoconazole, are usually fungistatic. This means that instead of directly killing fungi, they limit their growth and depend on natural processes to eliminate infection from the body.
When used in higher doses, they can become fungicides and attack cell membranes. Funguistic drugs are used more often as they tend to be safer, but may not be a good option for treating life-threatening infections or when the immune function of the dog is reduced.
Ketoconazole in dogs side effects is an antifungal drug effective against fungi of lymph nodes
- 1 Ketoconazole in dogs side effects is an antifungal drug effective against fungi of lymph nodes
The chosen dose and form of Ketoconazole depend to a large extent on the condition being treated and the actions required.
In most cases of external fungal infection can be applied topically. It must be applied enough to adequately cover the infected site.
For internal infection is given in pill form and often begins with a dose of 2.2 mg / pound twice a day this is a common dose for the treatment of systemic coccidioidomics.
For some conditions, the dose of the pill can be as high as 10 mg / lb or more. For safety reasons, you should not start administering this medication unless your veterinarian has advised you to do so. You should wear gloves when using the topical form and wash your hands carefully after the application.
Giving Ketoconazole with food can help with absorption and reduce stomach upset.
How it works, then simple, Ketoconazole acts by inhibiting the production of fungal cell wall, this makes the fungus structurally inadequate to escape and die, in smaller doses, Ketoconazole in dogs can be used to inhibit reproduction of the fungus.
It should be stored in a hermetically sealed container at room temperature and protected from heat or light., Administer the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give your pet two doses at a time.
Other forms of Ketoconazole in dogs dosage is itraconazole and fluconazole, have been produced to improve the number of side effects
Ketoconazole in dogs can cause these side effects such as inhibited synthesis of cortisone, dizziness, vomiting, diarrhea, loss of appetite, bleeding from the mouth, sensitivity to light
Ketoconazole also blocks the synthesis of cortisone in the adrenal gland, which in some cases can be a harmful side effect, but when used correctly, it is an effective treatment against Cushing’s syndrome.
Ketoconazole can react with these drugs, Aminophylline, Cisapride, Astemizole, Triazolam, Cyclosporine, Methylprednisolone, Mitotane, Phenytoin sodium, Rifampin, Theophylline, Warfarin sodium, H2 blockers, Antacids
Never administer Ketoconazole to pregnant pets and use this medicine with caution with liver diseases or hepatitis.
Do not give ketoconazole to your dog unless you have permission from your veterinarian.
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Ketoconazole dose in dogs can cause these side effects such as inhibited synthesis of cortisone, dizziness, vomiting, diarrhea and loss of appetite.
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